REFLUX
Reflux is a concern for
parents after having a baby born with the birth defect esophageal
atresia. This is also true for babies born with esophageal
atresia (EA) with a tracheo-esophageal fistula (TEF).
Gastro-esophageal reflux
(GER) seems to go hand in hand with these two birth defects
and it is evident that gastro-esophageal reflux occurs after
the connection of the two esophageal ends and with the creation
of a new esophagus from another part of the body such as
the colon, stomach or small intestine.
Another group of patients
that are affected by gastro-esophageal reflux are babies
born with GERD. They have no birth defect that can be seen
but they have serious and life threatening episodes of vomiting,
coughing, gagging and wrenching.
GERD is an acronym that stands for gastro-esophageal reflux
disease. More babies are born with GERD than born with TEF/EA.
These babies born with
GERD also suffer through the same problems and symptoms
as babies born with TEF/EA or EA and need to be diagnosed
and treated for reflux.
Babies with gastro-esophageal
reflux disease (GERD) and either esophageal atresia (EA)
with or without a tracheo-esophageal fistula (TEF) have
the same symptoms such as cyanosis (skin turning blue) problems,
choking spells, persistent coughing, gagging and vomiting
spells that can last for minutes, hours or days. Some may
even have spells of projectile vomiting that can last for
minutes, hours or days.
Gastro-esophageal reflux
is a serious and dangerous problem if not caught and treated.
Gastro esophageal reflux causes many other problems such
as asthma, bronchitis, pneumonia, high blood pressure, lung
problems such as atelectasis which can all lead to death.
GERD was not understood
in babies for years as it was not understood in adults.
It was usually thought that adults who had reflux had a
hiatal hernia which is when the stomach pushes up into the
chest though the hole in the muscle called the diaphragm
that separates the chest cavity from the abdominal cavity.
The stomach does not belong in the chest and this caused
many problems.
Reflux is when the food
and liquid that is passed down into the stomach after swallowing
occurs is pushed back up into the esophagus. The stomach
has acid in it to help break down food and this mixture
of food and acid is pushed back into the esophagus and can
cause burning, gagging, choking spells as well as burns
to the esophagus.
This burning or pain is
called heartburn because patients complained of pain in
the chest area where the heart is. The esophagus goes through
an area of chest cavity where it is actually surrounded
by blood vessels of the heart and this is why patients complain
of chest pain because the esophagus is very near to the
heart in its anatomical position and patients thought that
it was their heart that was burning and or causing their
pain.
Reflux is a serious condition
and is most commonly treated with medication first. If medication
does not stop the problem than a second way is to try and
stop the reflux by an operation called a Nissen fundoplication.
The name Nissen is the name of the surgeon who invented
the operation and is an eponym for the operation. The medications
that are used to prevent reflux have specific characteristics
that act upon specific symptoms that lead to reflux. If
the medicine can stop the symptoms it is to the benefit
of the child. It is common for many different medications
to be tried. Even if one medicine seems to be working well,
it is not unusual for it to not work after a while and therefore
another medication will be tried.
In some cases reflux is
so serious that medication does nothing and surgery is the
only alternative. The operation that is done all over the
world and is the most common and successful operation is
the reflux operation called the Nissen Fundoplication.
The operation consists
of wrapping or folding part of the stomach called the fundus
around the esophagus 360 degrees tightly to prevent reflux
from backing up the esophagus and causing all the symptoms
such as burning, gagging, choking, wrenching and vomiting
to name a few.
By wrapping or folding
the fundus around the esophagus and sewing the two ends
together the wrapping closes off the lower esophagus just
enough by preventing food and acid from going backwards
up into the esophagus. The esophagus can still work normally
to let food and liquid pass down the esophagus into the
stomach.
The wrapping is to prevent
or stop the backflow or vomiting up of the contents of the
stomach after eating. This is the most common and successful
operation done for reflux in the world. There are many variations
to this with the name of the procedure or operation named
after the doctor who modified the operation by Dr. Nissen.
Some other names for reflux
operations or fundoplications are the Rossetti fundoplication,
Thal fundoplication, Belsey 4 fundoplication, Doer fundoplication,
Boix-ochoia fundoplication which are all modifications of
the Nissen. Some of the operations are incomplete wraps
of the fundus around the esophagus. What this means is that
instead of completely wrapping or folding the part of the
stomach called the fundus completely around the esophagus
the modifications are done by wrapping or folding the fundus
around the esophagus only 270 degrees. There are other operations
that wrap or fold the fundus 180 degrees. Most of these
procedures are named after the doctor who first did the
operation.
The operations can be
repeated and the results are usually good. There are occasions
when the wraps seem to come undone over and over and no
one seems to know why.
Some of the procedures
sew the fundus anterior (front) and others sew the fundus
posterior (back). They all have good and bad results to
them. Some prevent vomiting and hiccupping and for some
reason on occasion they don't work at all. The wrapping
or folding of the fundus becomes undone and the reflux starts
again.
Reflux is first treated
with the many different medication s and if the medications
don't prevent the reflux than the next step is to consider
one of the available types of surgery called the fundoplications.
This is major surgery on the abdomen with a large incision
and scarring after.
Since 1995 some doctors
have been doing the fundoplication by laparoscopy which
means they make small incisions in the abdomen and place
long thin metal tubes inside the abdomen that have a light
source to see what they are doing, and other tubes to sew
and wrap and irrigate or flush out the abdomen and vacuum
out the liquid inside. It is not a common operation but
it is gaining more popularity as more surgeons become more
familiar with this procedure and learn how to do it by going
to training classes.
Here is a
list of the most common medicines to treat reflux. Some
are medicines you can go to a store and buy called over
the counter medicine and others you need to go to a doctor
and get a prescription for.
- Tagamet also called Cimetadine
- Zantac also called Ranitidine
- Pepcid also called Famotidine
- Prilosec also called Omeprazole
- Prevacid also called Lansoprazole
- Reglan also called Metoclopramide
- Milk of Magnesia also called MOM
- Kaopectate
- Propulsid also called Cisapride
- Periactin
- Bethanecho
- Carafate also called Sucralfate
- Levsin also called Hyoscyamine
- Tums
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